Npy1r - neuropeptide Y receptor Y1 Gene

Also Known as Npyr; Y1-R; NPY1-R

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18166

About Npy1r

Chromosome 8: 67,149,844-67,159,444 forward strand.GRCm39:CM001001.3

This gene has 2 transcripts (splice variants), 145 orthologues, 55 paralogues and is associated with 73 phenotypes. Biased expression in bladder adult (RPKM 14.), cortex adult (RPKM 4.1) and 8 other tissues.

Summary

Enables pancreatic polypeptide receptor activity and peptide YY receptor activity. Acts upstream of or within several processes, including feeding behavior; glucose metabolic process; and sensory perception of pain. Predicted to be located in several cellular components, including axon; cytosol; and synaptic vesicle. Is expressed in several structures, including heart; immune system; lung; metanephros; and nervous system. Used to study obesity. Orthologous to human NPY1R (Neuropeptide Y Receptor Y1). [provided by Alliance of Genome Resources, Apr 2022]

Npy1r Products (2)

mRNA Protein Name
NM_001358955.1 NP_001345884.1 neuropeptide Y receptor type 1
NM_010934.4 NP_035064.1 neuropeptide Y receptor type 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables neuropeptide Y receptor activity IDA
IDA: Inferred from direct assay
10698177 MGI
enables pancreatic polypeptide receptor activity IDA
IDA: Inferred from direct assay
10698177 MGI
enables peptide YY receptor activity IDA
IDA: Inferred from direct assay
10698177 MGI
Biological Process GO Annotation Evidence Verweise Source
NOT acts upstream of or within feeding behavior IMP
IMP: Inferred from mutant phenotype
9861026 MGI
acts upstream of or within feeding behavior IMP
IMP: Inferred from mutant phenotype
9623984 MGI
acts upstream of or within glucose metabolic process IMP
IMP: Inferred from mutant phenotype
9861026 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
9623984 MGI
acts upstream of or within regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
9623984 MGI
acts upstream of or within regulation of multicellular organism growth IMP
IMP: Inferred from mutant phenotype
9861026 MGI
acts upstream of or within sensory perception of pain IMP
IMP: Inferred from mutant phenotype
11206547 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Npy1r Protein Structure

7tmA_NPY1R

7tmA_NPY1R: cd15395 (39 - 329)

7tmA_NPY1R

7tmA_NPY1R: cd15395 (40 - 66)

7tmA_NPY1R

7tmA_NPY1R: cd15395 (73 - 98)

7tmA_NPY1R

7tmA_NPY1R: cd15395 (111 - 141)

7tmA_NPY1R

7tmA_NPY1R: cd15395 (152 - 173)

7tmA_NPY1R

7tmA_NPY1R: cd15395 (206 - 235)

7tmA_NPY1R

7tmA_NPY1R: cd15395 (254 - 284)

7tmA_NPY1R

7tmA_NPY1R: cd15395 (297 - 322)

  • 0
  • 100
  • 200
  • 300
  • 382 a.a.
Protein Preferred Names Protein Names

neuropeptide Y receptor type 1

  • NPY-1 receptor

  • neuropeptide Y receptor subtype

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS09512 Npy1r Mouse Pre-designed siRNA Set A / Unkown
HY-RS09511 NPY1R Human Pre-designed siRNA Set A / Unkown
HY-RS09513 Npy1r Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Npy1r NCBI NCBI:4886