Numbl - numb-like Gene

Also Known as nbl

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18223

Summary

Involved in lateral ventricle development; neuroblast division in subventricular zone; and positive regulation of neurogenesis. Acts upstream of or within adherens junction organization and nervous system development. Located in cytoplasm. Is expressed in several structures, including central nervous system; peripheral nervous system ganglion; sensory organ; testis; and thymus. Orthologous to human NUMBL (NUMB like endocytic adaptor protein). [provided by Alliance of Genome Resources, Apr 2022]

Numbl Products (1)

mRNA Protein Name
NM_010950.2 NP_035080.2 numb-like protein

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within adherens junction organization IGI
IGI: Inferred from genetic interaction
17589506 MGI
acts upstream of or within axonogenesis IMP
IMP: Inferred from mutant phenotype
15598981 MGI
acts upstream of or within forebrain development IMP
IMP: Inferred from mutant phenotype
14687546 MGI
involved in lateral ventricle development IMP
IMP: Inferred from mutant phenotype
17174898 MGI
acts upstream of or within nervous system development IMP
IMP: Inferred from mutant phenotype
14687546 MGI
involved in neuroblast division in subventricular zone IMP
IMP: Inferred from mutant phenotype
17174898 MGI
acts upstream of or within neuroblast proliferation IGI
IGI: Inferred from genetic interaction
12410312 MGI
involved in positive regulation of neurogenesis IMP
IMP: Inferred from mutant phenotype
12410312 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
9169836 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

numb-like protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09682 NUMBL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22696 Numbl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29210 Numbl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Numbl NCBI NCBI:9253