Ovol1 - ovo like zinc finger 1 Gene

Also Known as Ovo1; movo1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18426

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including negative regulation of stem cell proliferation; negative regulation of transcription by RNA polymerase II; and regulation of meiotic cell cycle. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skin. Orthologous to human OVOL1 (ovo like transcriptional repressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ovol1 Products (1)

mRNA Protein Name
NM_019935.3 NP_064319.1 putative transcription factor Ovo-like 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
17049212 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
17311813 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
17311813 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within epidermis development IGI
IGI: Inferred from genetic interaction
24735878 MGI
acts upstream of or within epidermis development IMP
IMP: Inferred from mutant phenotype
9808631 MGI
acts upstream of or within germline cell cycle switching, mitotic to meiotic cell cycle IMP
IMP: Inferred from mutant phenotype
15716349 MGI
acts upstream of keratinocyte proliferation IGI
IGI: Inferred from genetic interaction
24735878 MGI
acts upstream of or within kidney development IMP
IMP: Inferred from mutant phenotype
17049212 MGI
acts upstream of meiotic cell cycle phase transition IMP
IMP: Inferred from mutant phenotype
15716349 MGI
acts upstream of or within mesoderm development IMP
IMP: Inferred from mutant phenotype
9808631 MGI
acts upstream of or within negative regulation of keratinocyte proliferation IGI
IGI: Inferred from genetic interaction
24735878 MGI
acts upstream of or within negative regulation of meiotic cell cycle phase transition IMP
IMP: Inferred from mutant phenotype
15716349 MGI
acts upstream of or within negative regulation of stem cell proliferation IGI
IGI: Inferred from genetic interaction
24735878 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15716349 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
17311813 MGI
acts upstream of or within skin development IMP
IMP: Inferred from mutant phenotype
17049212 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
9808631 MGI
acts upstream of stem cell proliferation IGI
IGI: Inferred from genetic interaction
24735878 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
9808631 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

putative transcription factor Ovo-like 1

  • OVO homolog-like 1

  • mOvo1a

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09883 OVOL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21007 Ovol1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27524 Ovol1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ovol1 NCBI NCBI:5017