Oxtr - oxytocin receptor Gene

Mus musculus

Also known as OTR

Gene ID: 18430 | Gene type: protein coding

About Oxtr

Chromosome 6: 112,450,644-112,466,904 reverse strand.GRCm39:CM000999.3

This gene has 2 transcripts (splice variants), 265 orthologues, 16 paralogues and is associated with 14 phenotypes. Biased expression in adrenal adult (RPKM 71.9), mammary gland adult (RPKM 22.4) and 3 other tissues.

Summary

Predicted to enable Oxytocin Receptor activity; peptide hormone binding activity; and Vasopressin Receptor activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within positive regulation of blood pressure. Predicted to be located in adherens junction; apical plasma membrane; and microvillus. Predicted to be integral component of plasma membrane. Is expressed in several structures, including adipose tissue; brain; genitourinary system; integumental system; and small intestine. Orthologous to human OXTR (Oxytocin Receptor). [provided by Alliance of Genome Resources, Apr 2022]

Oxtr Products(2)

mRNA	Protein	Name
NM_001081147.3	NP_001074616.1	oxytocin receptor isoform 1
NM_001410246.1	NP_001397175.1	oxytocin receptor isoform 2

Oxtr Protein Structure

7tmA_OT_R

0
100
200
300
388 a.a.

Protein Preferred Names

Protein Names

oxytocin receptor

OT-R

Related Agents

Pre-clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-108678	TC OT 39		/	Unkown
HY-P4990	Pro8-Oxytocin	Activator	/	Unkown
HY-P4990A	Pro8-Oxytocin TFA	Activator	/	Unkown
HY-P5017	(Val3,Pro8)-Oxytocin	Agonist	/	Unkown
HY-RS09894	OXTR Human Pre-designed siRNA Set A		/	Unkown
HY-RS09895	Oxtr Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS09896	Oxtr Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Oxtr	NCBI	NCBI:5021

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