P2ry1 - purinergic receptor P2Y, G-protein coupled 1 Gene

Also Known as P2Y1; P2y1r

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18441

About P2ry1

Chromosome 3: 60,910,216-60,916,403 forward strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 191 orthologues, 13 paralogues and is associated with 4 phenotypes. Ubiquitous expression in colon adult (RPKM 5.3), large intestine adult (RPKM 4.9) and 27 other tissues.

Summary

Predicted to enable several functions, including A1 Adenosine Receptor binding activity; G protein-coupled purinergic nucleotide receptor activity; and adenyl ribonucleotide binding activity. Acts upstream of or within cellular response to organic cyclic compound and positive regulation of ion transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and liver and biliary system. Orthologous to human P2RY1 (purinergic receptor P2Y1). [provided by Alliance of Genome Resources, Apr 2022]

P2ry1 Products (2)

mRNA Protein Name
NM_008772.5 NP_032798.1 P2Y purinoceptor 1
NM_001282016.1 NP_001268945.1 P2Y purinoceptor 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to organic cyclic compound IDA
IDA: Inferred from direct assay
23479225 MGI
acts upstream of establishment of localization in cell IGI
IGI: Inferred from genetic interaction
15914557 MGI
acts upstream of establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
15914557 MGI
acts upstream of monoatomic ion transport IGI
IGI: Inferred from genetic interaction
15914557 MGI
acts upstream of monoatomic ion transport IMP
IMP: Inferred from mutant phenotype
15914557 MGI
acts upstream of or within positive regulation of monoatomic ion transport IGI
IGI: Inferred from genetic interaction
15914557 MGI
acts upstream of or within positive regulation of monoatomic ion transport IMP
IMP: Inferred from mutant phenotype
15914557 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
15670583 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

P2ry1 Protein Structure

7tmA_P2Y1

7tmA_P2Y1: cd15377 (51 - 334)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (51 - 78)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (85 - 110)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (123 - 153)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (165 - 187)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (213 - 242)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (252 - 282)

7tmA_P2Y1

7tmA_P2Y1: cd15377 (302 - 327)

  • 0
  • 100
  • 200
  • 300
  • 373 a.a.
Protein Preferred Names Protein Names

P2Y purinoceptor 1

  • ADP receptor

  • ATP receptor

  • P2Y1 receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09914 P2RY1 Human Pre-designed siRNA Set A / Unkown
HY-RS09915 P2ry1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS09916 P2ry1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2ry1 NCBI NCBI:5028