Pax9 - paired box 9 Gene

Also Known as Pax-9

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18511

Summary

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and Cancer growth. Mice lacking this gene exhibit impaired development of organs, musculature and the skeleton, including absent and abnormally developed teeth, and neonatal lethality. Mutations in the human gene are associated with selective tooth agenesis-3. [provided by RefSeq, Sep 2015]

Pax9 Products (1)

mRNA Protein Name
NM_011041.3 NP_035171.1 paired box protein Pax-9

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
14607846 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
14607846 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15721141 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to growth factor stimulus IDA
IDA: Inferred from direct assay
9244299 MGI
acts upstream of or within endoderm development IMP
IMP: Inferred from mutant phenotype
11932925 MGI
acts upstream of or within face morphogenesis IGI
IGI: Inferred from genetic interaction
20123092 MGI
acts upstream of or within odontogenesis IGI
IGI: Inferred from genetic interaction
20123092 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
14607846 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
15024065 MGI
acts upstream of or within regulation of odontogenesis IGI
IGI: Inferred from genetic interaction
20123092 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

paired box protein Pax-9

  • paired box gene 9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10096 PAX9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174554 Human PAX9 mRNA / Unkown
HY-RS22269 Pax9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28792 Pax9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pax9 NCBI NCBI:5083