Prkcz - protein kinase C, zeta Gene

Mus musculus

Also known as Pkcz; zetaPKC; aPKCzeta; nPKC-zeta

Gene ID: 18762 | Gene type: protein coding

About Prkcz

Chromosome 4: 155,344,586-155,445,818 reverse strand.GRCm39:CM000997.3

This gene has 10 transcripts (splice variants), 205 orthologues, 9 paralogues and is associated with 22 phenotypes. Broad expression in cortex adult (RPKM 34.2), cerebellum adult (RPKM 31.5) and 19 other tissues.

Summary

Enables protein serine/threonine kinase activity. Involved in positive regulation of T-helper 2 cell differentiation and positive regulation of cytokine production. Acts upstream of or within several processes, including neuron projection extension; protein localization to plasma membrane; and protein phosphorylation. Located in several cellular components, including axon hillock; myelin sheath abaxonal region; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PRKCZ (protein kinase C zeta). [provided by Alliance of Genome Resources, Apr 2022]

Prkcz Products(3)

mRNA	Protein	Name
NM_001355178.1	NP_001342107.1	protein kinase C zeta type isoform c
NM_008860.3	NP_032886.2	protein kinase C zeta type isoform a
NM_001039079.2	NP_001034168.1	protein kinase C zeta type isoform b

Prkcz Protein Structure

PB1_aPKC

PKc_like

0
100
200
300
400
500
592 a.a.

Protein Preferred Names

Protein Names

protein kinase C zeta type

atypical protein kinase C

protein kinase C zeta subspecies

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS11141	PRKCZ Human Pre-designed siRNA Set A	/	Unkown
HY-RS11142	Prkcz Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS11143	Prkcz Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Prkcz	NCBI	NCBI:5590

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