Ppm1b - protein phosphatase 1B, magnesium dependent, beta isoform Gene

Also Known as PP2CB

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19043

Summary

Predicted to enable protein serine/threonine Phosphatase activity. Involved in N-terminal protein myristoylation and protein dephosphorylation. Located in cytosol and membrane. Is expressed in several structures, including blastocyst; early embryo; gonad; liver; and lung. Orthologous to human PPM1B (protein Phosphatase, Mg2+/Mn2+ dependent 1B). [provided by Alliance of Genome Resources, Apr 2022]

Ppm1b Products (16)

mRNA Protein Name
NM_001159496.2 NP_001152968.1 protein phosphatase 1B isoform 1
NM_001159497.1 NP_001152969.1 protein phosphatase 1B isoform 3
NM_001159498.3 NP_001152970.1 protein phosphatase 1B isoform 4
NM_001411569.1 NP_001398498.1 protein phosphatase 1B isoform 1
NM_001411570.1 NP_001398499.1 protein phosphatase 1B isoform 1
NM_001411571.1 NP_001398500.1 protein phosphatase 1B isoform 5
NM_001411572.1 NP_001398501.1 protein phosphatase 1B isoform 3
NM_001411573.1 NP_001398502.1 protein phosphatase 1B isoform 3
NM_001411574.1 NP_001398503.1 protein phosphatase 1B isoform 3
NM_001411576.1 NP_001398505.1 protein phosphatase 1B isoform 4
NM_001411577.1 NP_001398506.1 protein phosphatase 1B isoform 4
NM_001411578.1 NP_001398507.1 protein phosphatase 1B isoform 4
NM_001411579.1 NP_001398508.1 protein phosphatase 1B isoform 6
NM_001411580.1 NP_001398509.1 protein phosphatase 1B isoform 2
NM_001411581.1 NP_001398510.1 protein phosphatase 1B isoform 7
NM_011151.3 NP_035281.1 protein phosphatase 1B isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in N-terminal protein myristoylation IDA
IDA: Inferred from direct assay
23088624 MGI
involved in protein dephosphorylation IMP
IMP: Inferred from mutant phenotype
23088624 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
23088624 MGI
located in membrane IDA
IDA: Inferred from direct assay
23088624 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein phosphatase 1B

  • PP2C-beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-159521 HN252 Inhibitor 99.94% Unkown
HY-RS10961 PPM1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19472 Ppm1b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25965 Ppm1b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppm1b NCBI NCBI:5495