Ptgfr - prostaglandin F receptor Gene

Also Known as fp; PGF

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19220

About Ptgfr

Chromosome 3: 151,502,139-151,543,267 reverse strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 195 orthologues, 7 paralogues and is associated with 3 phenotypes. Biased expression in ovary adult (RPKM 14.), heart adult (RPKM 2.7) and 5 other tissues.

Summary

Predicted to enable prostaglandin F receptor activity. Involved in positive regulation of gene expression and response to estradiol. Acts upstream of or within negative regulation of apoptotic process and response to lipopolysaccharide. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in cloaca; genital tubercle; jaw; and viscerocranium. Orthologous to human PTGFR (prostaglandin F receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ptgfr Products (1)

mRNA Protein Name
NM_008966.3 NP_032992.1 prostaglandin F2-alpha receptor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
12606450 MGI
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
21668646 MGI
involved in response to estradiol IDA
IDA: Inferred from direct assay
10684792 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
15834430 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Ptgfr Protein Structure

7tmA_FP

7tmA_FP: cd15145 (26 - 315)

7tmA_FP

7tmA_FP: cd15145 (27 - 53)

7tmA_FP

7tmA_FP: cd15145 (65 - 91)

7tmA_FP

7tmA_FP: cd15145 (107 - 137)

7tmA_FP

7tmA_FP: cd15145 (149 - 171)

7tmA_FP

7tmA_FP: cd15145 (196 - 225)

7tmA_FP

7tmA_FP: cd15145 (241 - 271)

7tmA_FP

7tmA_FP: cd15145 (282 - 307)

  • 0
  • 100
  • 200
  • 300
  • 366 a.a.
Protein Preferred Names Protein Names

prostaglandin F2-alpha receptor

  • PGF receptor

  • PGF2-alpha receptor

  • prostaglandin F2alpha receptor

  • prostanoid FP receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11382 PTGFR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11383 Ptgfr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11384 Ptgfr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptgfr NCBI NCBI:5737