Ptprb - protein tyrosine phosphatase, receptor type, B Gene

Also Known as Ptpz; Rptpb; Veptp; VE-PTP; C130094E24; 3230402H02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19263

Summary

Predicted to enable Cadherin binding activity. Involved in angiogenesis and peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Is expressed in several structures, including cardiovascular system; central nervous system; embryo mesenchyme; genitourinary system; and liver. Orthologous to human PTPRB (protein tyrosine Phosphatase receptor type B). [provided by Alliance of Genome Resources, Apr 2022]

Ptprb Products (1)

mRNA Protein Name
NM_029928.2 NP_084204.2 receptor-type tyrosine-protein phosphatase beta precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10557082 MGI
Biological Process GO Annotation Evidence References Source
involved in angiogenesis IDA
IDA: Inferred from direct assay
19451274 MGI
involved in angiogenesis IMP
IMP: Inferred from mutant phenotype
16514057 MGI
involved in dephosphorylation IDA
IDA: Inferred from direct assay
10557082 MGI
involved in peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity IDA
IDA: Inferred from direct assay
26063811 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

receptor-type tyrosine-protein phosphatase beta

  • R-PTP-beta

  • protein-tyrosine phosphatase beta

  • vascular endothelial protein tyrosine phosphatase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11433 PTPRB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21705 Ptprb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28223 Ptprb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptprb NCBI NCBI:5787