Rad9a - RAD9 checkpoint clamp component A Gene

Also Known as Rad9

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19367

Summary

Predicted to enable 3'-5' exonuclease activity; SH3 domain binding activity; and enzyme binding activity. Acts upstream of or within mitotic intra-S DNA damage checkpoint signaling and positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Located in cytoplasm and nucleus. Is expressed in retina; testis; and thyroid gland. Orthologous to human RAD9A (RAD9 checkpoint clamp component A). [provided by Alliance of Genome Resources, Apr 2022]

Rad9a Products (1)

mRNA Protein Name
NM_011237.2 NP_035367.1 cell cycle checkpoint control protein RAD9A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15983387 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of intrinsic apoptotic signaling pathway in response to DNA damage IGI
IGI: Inferred from genetic interaction
15983387 MGI
acts upstream of intrinsic apoptotic signaling pathway in response to DNA damage IMP
IMP: Inferred from mutant phenotype
15983387 MGI
acts upstream of or within mitotic intra-S DNA damage checkpoint signaling IGI
IGI: Inferred from genetic interaction
9766521 MGI
acts upstream of or within positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage IGI
IGI: Inferred from genetic interaction
15983387 MGI
acts upstream of or within positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage IMP
IMP: Inferred from mutant phenotype
15983387 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15983387 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15983387 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell cycle checkpoint control protein RAD9A

  • DNA repair exonuclease rad9 homolog A

  • RAD9 homolog A

  • Rad9-like protein

  • mRAD9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11614 RAD9A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21718 Rad9a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28236 Rad9a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rad9a NCBI NCBI:5883