Rbbp6 - retinoblastoma binding protein 6, ubiquitin ligase Gene

Also Known as PACT; P2P-R; 4933422O15Rik; C030034J04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19647

Summary

Predicted to enable protein kinase binding activity and ubiquitin protein Ligase activity. Involved in ubiquitin-dependent protein catabolic process. Acts upstream of or within embryonic organ development; in utero embryonic development; and somite development. Predicted to be located in nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Predicted to colocalize with centrosome. Is expressed in left lung and right lung. Orthologous to human RBBP6 (RB binding protein 6, ubiquitin Ligase). [provided by Alliance of Genome Resources, Apr 2022]

Rbbp6 Products (4)

mRNA Protein Name
NM_001403082.1 NP_001390011.1 E3 ubiquitin-protein ligase RBBP6 isoform 3
NM_001403083.1 NP_001390012.1 E3 ubiquitin-protein ligase RBBP6 isoform 4
NM_011247.3 NP_035377.2 E3 ubiquitin-protein ligase RBBP6 isoform 1
NM_175023.4 NP_778188.1 E3 ubiquitin-protein ligase RBBP6 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within embryonic organ development IGI
IGI: Inferred from genetic interaction
17470788 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
17470788 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
17470788 MGI
acts upstream of or within somite development IMP
IMP: Inferred from mutant phenotype
17470788 MGI
involved in ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
24726359 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RBBP6

  • RING-type E3 ubiquitin transferase RBBP6

  • p53-associated cellular protein of testis

  • proliferation potential-related protein

  • protein P2P-R

  • retinoblastoma-binding protein 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11718 RBBP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21722 Rbbp6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28240 Rbbp6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbbp6 NCBI NCBI:5930