Trim27 - tripartite motif-containing 27 Gene

Also Known as Rfp; Gm19403

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19720

Summary

Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin-like protein transferase activity. Involved in innate immune response; negative regulation of viral transcription; and suppression of viral release by host. Acts upstream of or within negative regulation of transcription by RNA polymerase II and positive regulation of actin nucleation. Located in cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; liver; lung; and retina. Orthologous to human TRIM27 (tripartite motif containing 27). [provided by Alliance of Genome Resources, Apr 2022]

Trim27 Products (1)

mRNA Protein Name
NM_009054.3 NP_033080.2 zinc finger protein RFP

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Biological Process GO Annotation Evidence References Source
involved in innate immune response IDA
IDA: Inferred from direct assay
18248090 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
16007160 MGI
involved in negative regulation of viral transcription IDA
IDA: Inferred from direct assay
18248090 MGI
acts upstream of or within positive regulation of actin nucleation IGI
IGI: Inferred from genetic interaction
23452853 MGI
involved in suppression of viral release by host IDA
IDA: Inferred from direct assay
18248090 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11331580 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein RFP

  • RING-type E3 ubiquitin transferase TRIM27

  • ret finger protein

  • tripartite motif protein 27

  • tripartite motif-containing protein 27

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15032 TRIM27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19824 Trim27 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26320 Trim27 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim27 NCBI NCBI:5987