Rgs16 - regulator of G-protein signaling 16 Gene

Also Known as Rgsr; Rgs14

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19734

About Rgs16

Chromosome 1: 153,616,095-153,621,214 forward strand.GRCm39:CM000994.3

This gene has 1 transcript (splice variant), 179 orthologues, 23 paralogues and is associated with 11 phenotypes. Broad expression in liver E18 (RPKM 12.8), CNS E11.5 (RPKM 1.4) and 15 other tissues.

Summary

Enables GTPase activator activity. Involved in G protein-coupled receptor signaling pathway and positive regulation of GTPase activity. Is intrinsic component of membrane. Is expressed in several structures, including central nervous system; limb mesenchyme; lip; neural retina; and skeletal musculature. Orthologous to human RGS16 (regulator of G protein signaling 16). [provided by Alliance of Genome Resources, Apr 2022]

Rgs16 Products (1)

mRNA Protein Name
NM_011267.4 NP_035397.2 regulator of G-protein signaling 16

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
10373502 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18434540 MGI
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
10373502 MGI
involved in positive regulation of GTPase activity IDA
IDA: Inferred from direct assay
10373502 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
10373502 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Rgs16 Protein Structure

RGS_RGS16

RGS_RGS16: cd08710 (64 - 177)

  • 0
  • 100
  • 201 a.a.
Protein Preferred Names Protein Names

regulator of G-protein signaling 16

  • A28-RGS14P

  • RGS-R

  • retinal-specific RGS

  • retinally abundant regulator of G-protein signaling

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13509 CCG-50014 Inhibitor 99.62% Unkown
HY-U00431 CCG 203769 Inhibitor 98.97% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rgs16 NCBI NCBI:6004