Polr2a - polymerase (RNA) II (DNA directed) polypeptide A Gene

Also Known as Rpb1; 220kDa; Rpo2-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20020

Summary

Enables core promoter sequence-specific DNA binding activity. Predicted to be involved in DNA-templated transcription, termination; positive regulation of RNA splicing; and transcription by RNA polymerase II. Located in euchromatin and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human POLR2A (RNA polymerase II subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Polr2a Products (1)

mRNA Protein Name
NM_001291068.1 NP_001277997.1 DNA-directed RNA polymerase II subunit RPB1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
15601870 MGI
enables core promoter sequence-specific DNA binding IDA
IDA: Inferred from direct assay
22723415 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8692929 MGI
Cellular Component GO Annotation Evidence References Source
located in euchromatin IDA
IDA: Inferred from direct assay
22723415 MGI
located in nucleus IDA
IDA: Inferred from direct assay
26346254 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-directed RNA polymerase II subunit RPB1

  • DNA-directed RNA polymerase II subunit A

  • DNA-directed RNA polymerase III largest subunit

  • RNA polymerase II 1

  • RNA polymerase II subunit B1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-135646 Eleutheroside B1 Inhibitor 99.00% Unkown
HY-RS10842 POLR2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19802 Polr2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26298 Polr2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr2a NCBI NCBI:5430