SPNS3 - SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative) Gene

Also Known as SLC62A3; SLC63A3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 201305

About SPNS3

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:4,433,940-4,488,204 (from NCBI)

This gene has 6 transcripts (splice variants), 192 orthologues and 2 paralogues. Biased expression in bone marrow (RPKM 8.7), spleen (RPKM 1.4) and 4 other tissues.

Summary

Predicted to enable transmembrane transporter activity. Predicted to be involved in lipid transport and transmembrane transport. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

SPNS3 Products (2)

mRNA Protein Name
NM_001320449.2 NP_001307378.1 protein spinster homolog 3 isoform 2
NM_182538.5 NP_872344.3 protein spinster homolog 3 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SPNS3 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (54 - 414)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 512 a.a.
Protein Preferred Names Protein Names

protein spinster homolog 3

  • SPNS sphingolipid transporter 3 (putative)

SPNS3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SPNS3 Q6ZMD2 CLCC1 Homo sapiens Q96S66
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13692 SPNS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SPNS3 VGNC VGNC:99268
Mus musculus SPNS3 MGD MGI:1924827
Canis familiaris SPNS3 VGNC VGNC:53449
Rattus norvegicus SPNS3 RGD RGD:1561884
Others SPNS3 NCBI