Sel1l - sel-1 suppressor of lin-12-like (C. elegans) Gene
Also Known as Sel1h; mKIAA4137
Species: Mus musculus
Summary
Predicted to contribute to ubiquitin-protein transferase activity. Involved in ERAD pathway; protein secretion; and triglyceride metabolic process. Acts upstream of or within response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum. Predicted to be part of Derlin-1 retrotranslocation complex and Hrd1p ubiquitin Ligase ERAD-L complex. Is expressed in several structures, including genitourinary system; liver; neural tube; pancreas; and spleen. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human SEL1L (SEL1L adaptor subunit of ERAD E3 ubiquitin Ligase). [provided by Alliance of Genome Resources, Apr 2022]
Sel1l Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001039089.1 | NP_001034178.1 | protein sel-1 homolog 1 isoform a precursor |
| NM_011344.2 | NP_035474.1 | protein sel-1 homolog 1 isoform b precursor |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
protein sel-1 homolog 1 |
|
|