Sel1l - sel-1 suppressor of lin-12-like (C. elegans) Gene

Also Known as Sel1h; mKIAA4137

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20338

Summary

Predicted to contribute to ubiquitin-protein transferase activity. Involved in ERAD pathway; protein secretion; and triglyceride metabolic process. Acts upstream of or within response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum. Predicted to be part of Derlin-1 retrotranslocation complex and Hrd1p ubiquitin Ligase ERAD-L complex. Is expressed in several structures, including genitourinary system; liver; neural tube; pancreas; and spleen. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human SEL1L (SEL1L adaptor subunit of ERAD E3 ubiquitin Ligase). [provided by Alliance of Genome Resources, Apr 2022]

Sel1l Products (2)

mRNA Protein Name
NM_001039089.1 NP_001034178.1 protein sel-1 homolog 1 isoform a precursor
NM_011344.2 NP_035474.1 protein sel-1 homolog 1 isoform b precursor
Protein Preferred Names Protein Names

protein sel-1 homolog 1

  • Sel1 (suppressor of lin-12) 1 homolog

  • sel-1L

  • suppressor of lin-12-like protein 1

Orthologs Information

Species Symbol Source ID
Homo sapiens Sel1l NCBI NCBI:6400