Srsf5 - serine and arginine-rich splicing factor 5 Gene

Also Known as Sfrs5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20384

Summary

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding Other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. [provided by RefSeq, Nov 2016]

Srsf5 Products (10)

mRNA Protein Name
NM_001079694.3 NP_001073162.1 serine/arginine-rich splicing factor 5 isoform 1
NM_001079695.3 NP_001073163.1 serine/arginine-rich splicing factor 5 isoform 1
NM_001347415.2 NP_001334344.1 serine/arginine-rich splicing factor 5 isoform 2
NM_001347416.2 NP_001334345.1 serine/arginine-rich splicing factor 5 isoform 2
NM_001409833.1 NP_001396762.1 serine/arginine-rich splicing factor 5 isoform 3
NM_001409834.1 NP_001396763.1 serine/arginine-rich splicing factor 5 isoform 4
NM_001409835.1 NP_001396764.1 serine/arginine-rich splicing factor 5 isoform 5
NM_001409836.1 NP_001396765.1 serine/arginine-rich splicing factor 5 isoform 5
NM_001409837.1 NP_001396766.1 serine/arginine-rich splicing factor 5 isoform 2
NM_009159.4 NP_033185.2 serine/arginine-rich splicing factor 5 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RS domain binding IPI
IPI: Inferred from physical interaction
15798186 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18758164 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within response to wounding IDA
IDA: Inferred from direct assay
9857059 MGI
Cellular Component GO Annotation Evidence References Source
located in nuclear speck IDA
IDA: Inferred from direct assay
18758164 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/arginine-rich splicing factor 5

  • delayed-early protein HRS

  • pre-mRNA-splicing factor SRP40

  • splicing factor, arginine/serine-rich 5 (SRp40, HRS)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13796 SRSF5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22832 Srsf5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srsf5 NCBI NCBI:6430