Slc31a1 - solute carrier family 31, member 1 Gene

Also Known as Ctr1; 4930445G01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20529

Summary

Enables copper ion transmembrane transporter activity. Acts upstream of or within cellular copper ion homeostasis and copper ion import. Located in late endosome; plasma membrane; and recycling endosome. Is expressed in several structures, including adrenal gland; alimentary system; early embryo; nervous system; and nose. Orthologous to human SLC31A1 (solute carrier family 31 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc31a1 Products (1)

mRNA Protein Name
NM_175090.4 NP_780299.2 high affinity copper uptake protein 1
Molecular Function GO Annotation Evidence References Source
enables copper ion transmembrane transporter activity IDA
IDA: Inferred from direct assay
11391005 MGI
enables copper ion transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
12177073 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24167251 MGI
enables silver ion transmembrane transporter activity IDA
IDA: Inferred from direct assay
20569931 MGI
enables xenobiotic transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
12370430 MGI
Biological Process GO Annotation Evidence References Source
involved in angiogenesis IMP
IMP: Inferred from mutant phenotype
35027734 MGI
involved in copper ion import IDA
IDA: Inferred from direct assay
16950140 MGI
acts upstream of or within copper ion import IMP
IMP: Inferred from mutant phenotype
12177073 MGI
involved in copper ion import IMP
IMP: Inferred from mutant phenotype
16847145 MGI
involved in copper ion transport IDA
IDA: Inferred from direct assay
11391005 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
12177073 MGI
acts upstream of or within intracellular copper ion homeostasis IGI
IGI: Inferred from genetic interaction
24167251 MGI
involved in silver ion transmembrane transport IDA
IDA: Inferred from direct assay
20569931 MGI
involved in xenobiotic transport IMP
IMP: Inferred from mutant phenotype
12370430 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
16950140 MGI
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
19144690 MGI
located in intercalated disc IDA
IDA: Inferred from direct assay
28973536 MGI
located in late endosome IDA
IDA: Inferred from direct assay
24167251 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
28973536 MGI
located in recycling endosome IDA
IDA: Inferred from direct assay
24167251 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

high affinity copper uptake protein 1

  • copper transporter 1

  • solute carrier family 13 (sodium/sulphate symporters), member 1

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc31a1 NCBI NCBI:1317