Slc31a1 - solute carrier family 31, member 1 Gene
Also Known as Ctr1; 4930445G01Rik
Species: Mus musculus
Summary
Enables copper ion transmembrane transporter activity. Acts upstream of or within cellular copper ion homeostasis and copper ion import. Located in late endosome; plasma membrane; and recycling endosome. Is expressed in several structures, including adrenal gland; alimentary system; early embryo; nervous system; and nose. Orthologous to human SLC31A1 (solute carrier family 31 member 1). [provided by Alliance of Genome Resources, Apr 2022]
Slc31a1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_175090.4 | NP_780299.2 | high affinity copper uptake protein 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables copper ion transmembrane transporter activity |
IDA
IDA: Inferred from direct assay
|
11391005 | MGI |
| enables copper ion transmembrane transporter activity |
IMP
IMP: Inferred from mutant phenotype
|
12177073 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
24167251 | MGI |
| enables silver ion transmembrane transporter activity |
IDA
IDA: Inferred from direct assay
|
20569931 | MGI |
| enables xenobiotic transmembrane transporter activity |
IMP
IMP: Inferred from mutant phenotype
|
12370430 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in angiogenesis |
IMP
IMP: Inferred from mutant phenotype
|
35027734 | MGI |
| involved in copper ion import |
IDA
IDA: Inferred from direct assay
|
16950140 | MGI |
| acts upstream of or within copper ion import |
IMP
IMP: Inferred from mutant phenotype
|
12177073 | MGI |
| involved in copper ion import |
IMP
IMP: Inferred from mutant phenotype
|
16847145 | MGI |
| involved in copper ion transport |
IDA
IDA: Inferred from direct assay
|
11391005 | MGI |
| acts upstream of or within establishment of localization in cell |
IMP
IMP: Inferred from mutant phenotype
|
12177073 | MGI |
| acts upstream of or within intracellular copper ion homeostasis |
IGI
IGI: Inferred from genetic interaction
|
24167251 | MGI |
| involved in silver ion transmembrane transport |
IDA
IDA: Inferred from direct assay
|
20569931 | MGI |
| involved in xenobiotic transport |
IMP
IMP: Inferred from mutant phenotype
|
12370430 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in apical plasma membrane |
IDA
IDA: Inferred from direct assay
|
16950140 | MGI |
| located in basolateral plasma membrane |
IDA
IDA: Inferred from direct assay
|
19144690 | MGI |
| located in intercalated disc |
IDA
IDA: Inferred from direct assay
|
28973536 | MGI |
| located in late endosome |
IDA
IDA: Inferred from direct assay
|
24167251 | MGI |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
28973536 | MGI |
| located in recycling endosome |
IDA
IDA: Inferred from direct assay
|
24167251 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
high affinity copper uptake protein 1 |
|