Siglec1 - sialic acid binding Ig-like lectin 1, sialoadhesin Gene

Also Known as Sn; Cd169; Siglec-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20612

Summary

Predicted to enable virion binding activity. Acts upstream of or within positive regulation of T cell apoptotic process and positive regulation of extrinsic apoptotic signaling pathway. Predicted to be located in extracellular region and membrane. Predicted to be integral component of membrane. Predicted to be active in early endosome; late endosome; and plasma membrane. Is expressed in immune system; reproductive system; and skin. Orthologous to human SIGLEC1 (sialic acid binding Ig like lectin 1). [provided by Alliance of Genome Resources, Apr 2022]

Siglec1 Products (1)

mRNA Protein Name
NM_011426.3 NP_035556.3 sialoadhesin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11238599 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of T cell apoptotic process IMP
IMP: Inferred from mutant phenotype
23408841 MGI
acts upstream of or within positive regulation of extrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
23408841 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sialoadhesin

  • SER

  • sheep erythrocyte receptor

  • sialic acid-binding Ig-like lectin 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12897 SIGLEC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18016 Siglec1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24489 Siglec1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Siglec1 NCBI NCBI:6614