Sod3 - superoxide dismutase 3, extracellular Gene

Also Known as EC-SOD

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20657

Summary

Enables superoxide dismutase activity. Acts upstream of or within response to hypoxia. Located in extracellular space. Colocalizes with collagen-containing extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and neural ectoderm. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3). [provided by Alliance of Genome Resources, Apr 2022]

Sod3 Products (1)

mRNA Protein Name
NM_011435.3 NP_035565.1 extracellular superoxide dismutase [Cu-Zn] precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16371425 MGI
enables superoxide dismutase activity IDA
IDA: Inferred from direct assay
16371425 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within response to hypoxia IMP
IMP: Inferred from mutant phenotype
15016652 MGI
Cellular Component GO Annotation Evidence References Source
colocalizes with collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
15528465 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
15016652 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

extracellular superoxide dismutase [Cu-Zn]

  • extracellular superoxide dismutase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-136651 BNTA 99.48% Unkown
HY-RS13561 SOD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17818 Sod3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24287 Sod3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sod3 NCBI NCBI:6649