2. Gene
  3. D130043K22Rik - RIKEN cDNA D130043K22 gene Gene

D130043K22Rik - RIKEN cDNA D130043K22 gene Gene

  • Gene
  • Protein
Mus musculus

Also known as Kiaa0319; 4930451E12Rik

Gene ID: 210108 | Gene type: protein coding

About D130043K22Rik

Summary

This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in a similar gene in human are associated with dyslexia. Alternatively spliced transcript variants have been identifed. [provided by RefSeq, May 2015]

D130043K22Rik Products(1)

mRNA Protein Name
NM_001081051.2 NP_001074520.1 dyslexia-associated protein KIAA0319 homolog precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within central nervous system neuron development IMP
IMP: Inferred from mutant phenotype
35419947 MGI
acts upstream of or within multicellular organismal response to stress IMP
IMP: Inferred from mutant phenotype
27510895 MGI
acts upstream of or within negative regulation of axon extension involved in regeneration IMP
IMP: Inferred from mutant phenotype
28334068 MGI
NOT acts upstream of or within neurogenesis IMP
IMP: Inferred from mutant phenotype
27510895 MGI
NOT acts upstream of or within neuron migration IGI
IGI: Inferred from genetic interaction
29045729 MGI
NOT acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
27510895 MGI
acts upstream of or within response to auditory stimulus IGI
IGI: Inferred from genetic interaction
29045729 MGI
acts upstream of or within response to auditory stimulus IMP
IMP: Inferred from mutant phenotype
35419947 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
35419947 MGI
acts upstream of or within thalamus development IMP
IMP: Inferred from mutant phenotype
35419947 MGI
acts upstream of or within vocal learning IMP
IMP: Inferred from mutant phenotype
35419947 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dyslexia-associated protein KIAA0319 homolog