Dstyk - dual serine/threonine and tyrosine protein kinase Gene

Also Known as Ripk5; C820013G01; A930019K20Rik; C430014H23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 213452

Summary

Predicted to enable ATP binding activity and protein kinase activity. Predicted to be involved in several processes, including cellular response to Fibroblast Growth Factor stimulus; positive regulation of kinase activity; and positive regulation of signal transduction. Predicted to act upstream of or within phosphorylation. Located in apical plasma membrane; basolateral plasma membrane; and cytoplasm. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and skin. Human ortholog(s) of this gene implicated in CAKUT1 and hereditary spastic paraplegia 23. Orthologous to human DSTYK (dual serine/threonine and tyrosine protein kinase). [provided by Alliance of Genome Resources, Apr 2022]

Dstyk Products (1)

mRNA Protein Name
NM_172516.4 NP_766104.2 dual serine/threonine and tyrosine protein kinase

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
23862974 MGI
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
23862974 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
23862974 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual serine/threonine and tyrosine protein kinase

  • dusty PK

  • dusty protein kinase

  • receptor interacting protein kinase 5

  • receptor-interacting serine/threonine-protein kinase 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04030 DSTYK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22473 Dstyk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dstyk NCBI NCBI:25778