Trim38 - tripartite motif-containing 38 Gene

Also Known as Gm23

Species: Mus musculus

Gene Type: protein coding
Gene ID: 214158

Summary

Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin protein Ligase activity. Acts upstream of or within several processes, including cellular protein metabolic process; negative regulation of defense response to virus; and positive regulation of viral genome replication. Predicted to be active in cytosol and nucleoplasm. Orthologous to human TRIM38 (tripartite motif containing 38). [provided by Alliance of Genome Resources, Apr 2022]

Trim38 Products (1)

mRNA Protein Name
NM_001029935.2 NP_001025106.1 E3 ubiquitin-protein ligase TRIM38

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22539786 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
26392463 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of defense response to virus IMP
IMP: Inferred from mutant phenotype
22539786 MGI
acts upstream of or within positive regulation of viral genome replication IDA
IDA: Inferred from direct assay
22539786 MGI
acts upstream of or within positive regulation of viral genome replication IMP
IMP: Inferred from mutant phenotype
22539786 MGI
acts upstream of or within proteasome-mediated ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
22539786 MGI
acts upstream of or within proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
22539786 MGI
acts upstream of or within protein K48-linked ubiquitination IDA
IDA: Inferred from direct assay
22539786 MGI
acts upstream of or within protein K48-linked ubiquitination IMP
IMP: Inferred from mutant phenotype
22539786 MGI
acts upstream of or within regulation of interferon-beta production IDA
IDA: Inferred from direct assay
22539786 MGI
acts upstream of or within regulation of interferon-beta production IMP
IMP: Inferred from mutant phenotype
22539786 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM38

  • E3 SUMO-protein ligase TRIM38

  • RING finger protein 15

  • tripartite motif-containing protein 38

  • zinc finger protein RoRet

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15042 TRIM38 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21961 Trim38 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28478 Trim38 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim38 NCBI NCBI:10475