Tcp1 - t-complex protein 1 Gene

Also Known as CCT; p63; Cct1; Ccta; TRic; Tp63; Tcp-1; c-cpn

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21454

Summary

Predicted to enable protein folding chaperone; ubiquitin protein Ligase binding activity; and unfolded protein binding activity. Acts upstream of or within several processes, including binding activity of sperm to zona pellucida; toxin transport; and translocation of peptides or proteins into host cell cytoplasm. Located in several cellular components, including acrosomal vesicle; heterochromatin; and pericentriolar material. Part of chaperonin-containing T-complex and zona pellucida receptor complex. Is expressed in several structures, including cerebral cortex; extraembryonic component; genitourinary system; humerus; and immune system. Orthologous to human TCP1 (t-complex 1). [provided by Alliance of Genome Resources, Apr 2022]

Tcp1 Products (2)

mRNA Protein Name
NM_001290712.1 NP_001277641.1 T-complex protein 1 subunit alpha isoform 2
NM_013686.4 NP_038714.2 T-complex protein 1 subunit alpha isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11163258 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within binding of sperm to zona pellucida IDA
IDA: Inferred from direct assay
21880732 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
2655925 MGI
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
2655925 MGI
located in cell body IDA
IDA: Inferred from direct assay
21880732 MGI
part of chaperonin-containing T-complex IDA
IDA: Inferred from direct assay
7828721 MGI
located in heterochromatin IDA
IDA: Inferred from direct assay
12915127 MGI
located in microtubule organizing center IDA
IDA: Inferred from direct assay
12915127 MGI
located in pericentriolar material IDA
IDA: Inferred from direct assay
12915127 MGI
part of zona pellucida receptor complex IDA
IDA: Inferred from direct assay
21880732 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

T-complex protein 1 subunit alpha

  • CCT-alpha

  • T-complex protein 1 subunit alpha A

  • T-complex protein 1 subunit alpha B

  • TCP-1-A

  • TCP-1-B

  • TCP-1-alpha

  • t-complex polypeptide 1

  • tailless complex polypeptide 1A

  • tailless complex polypeptide 1B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103000 HSF1A Activator 99.94% Unkown
HY-RS14321 TCP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19962 Tcp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26464 Tcp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tcp1 NCBI NCBI:6950