Rap1b - RAS related protein 1b Gene

Also Known as 2810443E11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 215449

Summary

Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Acts upstream of or within several processes, including negative regulation of regulated secretory pathway; positive regulation of ERK1 and ERK2 cascade; and small GTPase mediated signal transduction. Predicted to be located in cell-cell junction; cytosol; and lipid droplet. Predicted to be active in plasma membrane. Is expressed in brain and cerebral cortex. Orthologous to human RAP1B (RAP1B, member of Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rap1b Products (1)

mRNA Protein Name
NM_024457.2 NP_077777.1 ras-related protein Rap-1b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables G protein activity IDA
IDA: Inferred from direct assay
11056535 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14712229 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of calcium-ion regulated exocytosis IGI
IGI: Inferred from genetic interaction
23616533 MGI
acts upstream of or within cell population proliferation IPI
IPI: Inferred from physical interaction
14712229 MGI
acts upstream of establishment of localization in cell IGI
IGI: Inferred from genetic interaction
23616533 MGI
involved in modification of postsynaptic structure IDA
IDA: Inferred from direct assay
26844834 MGI
involved in modification of postsynaptic structure IMP
IMP: Inferred from mutant phenotype
26844834 MGI
acts upstream of or within negative regulation of calcium ion-dependent exocytosis IGI
IGI: Inferred from genetic interaction
23616533 MGI
acts upstream of or within negative regulation of synaptic vesicle exocytosis IGI
IGI: Inferred from genetic interaction
23616533 MGI
acts upstream of or within positive regulation of ERK1 and ERK2 cascade IGI
IGI: Inferred from genetic interaction
23616533 MGI
acts upstream of or within small GTPase-mediated signal transduction IDA
IDA: Inferred from direct assay
14712229 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
26844834 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
26844834 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rap-1b

  • GTP-binding protein smg p21B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-180801 E8431 97.34% Unkown
HY-RS16301 Rap1b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11653 RAP1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29280 Rap1b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rap1b NCBI NCBI:5908