Tsc22d1 - TSC22 domain family, member 1 Gene

Also Known as Tsc; Egr5; Tsc22; TSC-22; Gm19597; Tgfb1i4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21807

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of apoptotic process; positive regulation of apoptotic process; and positive regulation of cell population proliferation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Orthologous to human TSC22D1 (TSC22 domain family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Tsc22d1 Products (5)

mRNA Protein Name
NM_001177751.2 NP_001171222.1 TSC22 domain family protein 1 isoform 3
NM_001310646.1 NP_001297575.1 TSC22 domain family protein 1 isoform 4
NM_001310647.1 NP_001297576.1 TSC22 domain family protein 1 isoform 5
NM_009366.4 NP_033392.1 TSC22 domain family protein 1 isoform 2
NM_207652.3 NP_997535.2 TSC22 domain family protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20713358 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of hematopoietic stem cell proliferation IMP
IMP: Inferred from mutant phenotype
19329776 MGI
acts upstream of negative regulation of programmed cell death IMP
IMP: Inferred from mutant phenotype
19745830 MGI
acts upstream of positive regulation of programmed cell death IMP
IMP: Inferred from mutant phenotype
19745830 MGI
acts upstream of positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
20713358 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19745830 MGI
located in nucleus IDA
IDA: Inferred from direct assay
19745830 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TSC22 domain family protein 1

  • Tgfb-stimulated clone 22 homolog

  • Tsc22-related inducible leucine zipper 1b

  • regulatory protein Tsc22

  • transforming growth factor beta 1 induced transcript 4

Recombinant Tsc22d1 Proteins

Cat. No. Product Name Accession Purity
HY-P77259 TSC22/TSC22D1 Protein, Mouse (His) NP_033392 (M1-A143) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15133 TSC22D1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19556 Tsc22d1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26052 Tsc22d1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tsc22d1 NCBI NCBI:8848