2. Gene
  3. Tgfbr3 - transforming growth factor, beta receptor III Gene

Tgfbr3 - transforming growth factor, beta receptor III Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TBRIII; 1110036H20Rik

Gene ID: 21814 | Gene type: protein coding

About Tgfbr3

Chromosome 5: 107,254,436-107,437,495 reverse strand.GRCm39:CM000998.3

This gene has 4 transcripts (splice variants), 203 orthologues, 2 paralogues and is associated with 52 phenotypes. Broad expression in adrenal adult (RPKM 38.6), bladder adult (RPKM 2.1) and 2 other tissues.

Summary

Enables several functions, including PDZ domain binding activity; transforming growth factor beta binding activity; and transforming growth factor beta-activated receptor activity. Involved in several processes, including definitive erythrocyte differentiation; heart development; and transmembrane receptor protein serine/threonine kinase signaling pathway. Acts upstream of or within several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and vasculogenesis. Located in cell surface and endoplasmic reticulum. Is expressed in several structures, including brain; early conceptus; heart; lower jaw; and ovary. Orthologous to human TGFBR3 (transforming growth factor beta receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Tgfbr3 Products(1)

mRNA Protein Name
NM_011578.4 NP_035708.2 transforming growth factor beta receptor type 3 precursor

Tgfbr3 Protein Structure

ZP

ZP: smart00241 (453 - 722)

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  • 850 a.a.
Protein Preferred Names Protein Names

transforming growth factor beta receptor type 3

TGF-beta receptor type 3

TGF-beta receptor type III

TGFR-3

betaglycan

Recombinant Tgfbr3 Proteins

Cat. No. Product Name Accession Purity
HY-P72452 TGFBR3/TGF-beta RIII Protein, Mouse (763a.a, HEK293, His) A0A0R4J097 (G23-T785) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14450 TGFBR3 Human Pre-designed siRNA Set A / Unkown
HY-RS14451 Tgfbr3 Mouse Pre-designed siRNA Set A / Unkown
HY-RS14452 Tgfbr3 Rat Pre-designed siRNA Set A / Unkown
HY-RS14453 TGFBR3L Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tgfbr3 NCBI NCBI:7049