NT5DC1 - 5'-nucleotidase domain containing 1 Gene

Also Known as LP2642; NT5C2L1; C6orf200

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 221294

About NT5DC1

This gene has 4 transcripts (splice variants), 209 orthologues and 4 paralogues. Ubiquitous expression in thyroid (RPKM 16.7), prostate (RPKM 14.4) and 25 other tissues.

Summary

While the exact function of the protein encoded by this gene is not known, it belongs to the 5'(3')-deoxyribonucleotidase family. [provided by RefSeq, May 2010]

NT5DC1 Products (1)

mRNA	Protein	Name
NM_152729.3	NP_689942.2	5'-nucleotidase domain-containing protein 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NT5DC1 Protein Structure

5_nucleotid

0
100
200
300
400
455 a.a.

Protein Preferred Names	Protein Names
5'-nucleotidase domain-containing protein 1	5'-nucleotidase, cytosolic II-like 1 protein

NT5DC1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	NT5DC1	Q5TFE4	HSP90AA4P	Homo sapiens	Q58FG1	Anti Tag CoIP	33961781
Intra	NT5DC1	Q5TFE4	HSP90AA4P	Homo sapiens	Q58FG1	Anti Tag CoIP	28514442

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Metaphyseal Chondrodysplasia, Schmid Type	MCDS Schmid Metaphyseal Chondrodysplasia Metaphyseal Chondrodysplasia Schmid Type Spondylometaphyseal Dysplasia, Japanese Type Japanese Type Spondylometaphyseal Dysplasia Schmid Type Metaphyseal Dysplasia Metaphyseal Chondrodysplasia Type Schmid Schmid Type Metaphyseal Chondrodysplasia SMCD Chondrodysplasia, Metaphyseal, Schmid Type Corneal Dystrophy, Subepithelial Mucinous
Spastic Paraplegia 45, Autosomal Recessive	SPG45 Hereditary Spastic Paraplegia 45 Autosomal Recessive Spastic Paraplegia Type 45 Autosomal Recessive Spastic Paraplegia Type 65 Spg65 Autosomal Recessive Spastic Paraplegia 45 Paraplegia, Spastic, Type 45, Autosomal Recessive

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09610	NT5DC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	NT5DC1	MGD	MGI:2442446
Macaca mulatta	NT5DC1	VGNC	VGNC:81189
Rattus norvegicus	NT5DC1	RGD	RGD:1305214
Canis familiaris	NT5DC1	VGNC	VGNC:54336
Bos taurus	NT5DC1	VGNC	VGNC:32294
Felis catus	NT5DC1	VGNC	VGNC:63899
Others	NT5DC1	NCBI