Uty - ubiquitously transcribed tetratricopeptide repeat containing, Y-linked Gene

Also Known as Hydb; mKIAA4057

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22290

Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and histone H3-methyl-lysine-36 demethylase activity. Acts upstream of or within several processes, including animal organ development; cardiac muscle cell contraction; and heterochromatin assembly. Part of protein-containing complex. Is expressed in several structures, including early conceptus; forelimb bud; genitourinary system; gut; and liver. Orthologous to human UTY (ubiquitously transcribed tetratricopeptide repeat containing, Y-linked). [provided by Alliance of Genome Resources, Apr 2022]

Uty Products (6)

mRNA Protein Name
NM_001326682.1 NP_001313611.1 histone demethylase UTY isoform 2
NM_001326683.1 NP_001313612.1 histone demethylase UTY isoform 3
NM_009484.3 NP_033510.2 histone demethylase UTY isoform 1
NM_001326682.1 NP_001313611.1 histone demethylase UTY isoform 2
NM_001326683.1 NP_001313612.1 histone demethylase UTY isoform 3
NM_009484.3 NP_033510.2 histone demethylase UTY isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
22949634 MGI
enables histone H3K36 demethylase activity IMP
IMP: Inferred from mutant phenotype
22192413 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22192413 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cardiac muscle cell contraction IMP
IMP: Inferred from mutant phenotype
22192413 MGI
acts upstream of or within embryonic organ development IMP
IMP: Inferred from mutant phenotype
23028370 MGI
acts upstream of or within establishment of protein localization IDA
IDA: Inferred from direct assay
22192413 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
22192413 MGI
acts upstream of or within heart morphogenesis IMP
IMP: Inferred from mutant phenotype
23028370 MGI
acts upstream of or within heterochromatin formation IMP
IMP: Inferred from mutant phenotype
22192413 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
22192413 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
23028370 MGI
Cellular Component GO Annotation Evidence References Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
23028370 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone demethylase UTY

  • [histone H3]-trimethyl-L-lysine(27) demethylase UTY

  • male-specific histocompatibility antigen H-YDB

  • ubiquitously transcribed TPR protein on the Y chromosome

  • ubiquitously transcribed Y chromosome tetratricopeptide repeat protein

  • ubiquitously transcribed

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15587 UTY Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17629 Uty Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24089 Uty Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uty NCBI NCBI:7404