Trio - triple functional domain (PTPRF interacting) Gene

Also Known as Solo; 6720464I07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 223435

Summary

Predicted to enable enzyme binding activity and guanyl-nucleotide exchange factor activity. Involved in negative regulation of fat cell differentiation. Predicted to be located in cell projection and endosome. Predicted to be active in cytoplasm. Predicted to be extrinsic component of membrane. Is expressed in central nervous system and dorsal root ganglion. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability and autosomal dominant non-syndromic intellectual disability 44. Orthologous to human TRIO (trio Rho guanine nucleotide exchange factor). [provided by Alliance of Genome Resources, Apr 2022]

Trio Products (1)

mRNA Protein Name
NM_001081302.1 NP_001074771.1 triple functional domain protein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of fat cell differentiation IMP
IMP: Inferred from mutant phenotype
22666460 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

triple functional domain protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS24288 Trio Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trio NCBI NCBI:7204