Nae1 - NEDD8 activating enzyme E1 subunit 1 Gene

Also Known as 59kDa; Appbp1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 234664

Summary

Predicted to enable NEDD8 activating enzyme activity; protein heterodimerization activity; and ubiquitin protein Ligase binding activity. Predicted to be involved in several processes, including mitotic DNA replication checkpoint signaling; neuron apoptotic process; and protein neddylation. Predicted to act upstream of or within apoptotic process. Predicted to be located in early endosome and membrane raft. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm. Is expressed in central nervous system and retina. Orthologous to human NAE1 (NEDD8 activating enzyme E1 subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Nae1 Products (1)

mRNA Protein Name
NM_144931.3 NP_659180.1 NEDD8-activating enzyme E1 regulatory subunit
Protein Preferred Names Protein Names

NEDD8-activating enzyme E1 regulatory subunit

  • APP-BP1

  • amyloid beta precursor protein binding protein 1, 59kDa

  • amyloid beta precursor protein-binding protein 1, 59 kDa

  • amyloid protein-binding protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-133558 VII-31 99.63% Unkown
HY-161268 NAE-IN-1 99.75% Unkown
HY-RS09007 NAE1 Human Pre-designed siRNA Set A / Unkown
HY-RS17023 Nae1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23466 Nae1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nae1 NCBI NCBI:8883