Dnajb6 - DnaJ heat shock protein family (Hsp40) member B6 Gene

Also Known as Mrj; mDj4; HSJ-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23950

Summary

Enables DNA binding activity. Acts upstream of or within several processes, including chorion development; labyrinthine layer development; and protein localization to nucleus. Located in cytoplasm and nucleus. Is expressed in several structures, including extraembryonic component; hemolymphoid system; nervous system; reproductive system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 1. Orthologous to human DNAJB6 (DnaJ heat shock protein family (HSP40) member B6). [provided by Alliance of Genome Resources, Apr 2022]

Dnajb6 Products (6)

mRNA Protein Name
NM_001037940.4 NP_001033029.1 dnaJ homolog subfamily B member 6 isoform a
NM_001037941.3 NP_001033030.2 dnaJ homolog subfamily B member 6 isoform b
NM_001127367.1 NP_001120839.1 dnaJ homolog subfamily B member 6 isoform d
NM_001359198.1 NP_001346127.1 dnaJ homolog subfamily B member 6 isoform e
NM_001378835.1 NP_001365764.1 dnaJ homolog subfamily B member 6 isoform f
NM_011847.4 NP_035977.2 dnaJ homolog subfamily B member 6 isoform c

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
16260608 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
21972064 MGI
acts upstream of or within chorio-allantoic fusion IMP
IMP: Inferred from mutant phenotype
10021343 MGI
acts upstream of or within chorion development IMP
IMP: Inferred from mutant phenotype
21972064 MGI
acts upstream of or within extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
21972064 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
16260608 MGI
acts upstream of or within protein localization to nucleus IMP
IMP: Inferred from mutant phenotype
18373498 MGI
acts upstream of or within syncytiotrophoblast cell differentiation involved in labyrinthine layer development IMP
IMP: Inferred from mutant phenotype
21972064 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16260608 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16260608 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dnaJ homolog subfamily B member 6

  • DnaJ (Hsp40) homolog, subfamily B, member 6

  • heat shock protein J2

  • mammalian relative of DnaJ

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03869 DNAJB6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21116 Dnajb6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27635 Dnajb6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnajb6 NCBI NCBI:10049