Nek3 - NIMA (never in mitosis gene a)-related expressed kinase 3 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23954

Summary

Predicted to enable ATP binding activity; metal ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including neuron projection morphogenesis; protein phosphorylation; and regulation of tubulin deacetylation. Predicted to be located in cell projection and cytoplasm. Is expressed in several structures, including brain; genitourinary system; intestine; and spleen. Orthologous to human NEK3 (NIMA Related Kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Nek3 Products (2)

mRNA Protein Name
NM_001162947.1 NP_001156419.1 serine/threonine-protein kinase Nek3 isoform 1
NM_011848.4 NP_035978.2 serine/threonine-protein kinase Nek3 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in establishment of cell polarity IMP
IMP: Inferred from mutant phenotype
19509051 MGI
involved in neuron projection morphogenesis IMP
IMP: Inferred from mutant phenotype
19509051 MGI
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
19509051 MGI
involved in regulation of tubulin deacetylation IMP
IMP: Inferred from mutant phenotype
19509051 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase Nek3

  • NIMA-related expressed kinase 3

  • never in mitosis A-related kinase 3

  • nimA-related protein kinase 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09194 NEK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20306 Nek3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26814 Nek3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nek3 NCBI NCBI:4752