Mief1 - mitochondrial elongation factor 1 Gene

Mus musculus

Also known as Smcr7l; A230016E22

Gene ID: 239555 | Gene type: protein coding

About Mief1

Summary

Enables identical protein binding activity. Involved in positive regulation of mitochondrial fission. Located in mitochondrion. Orthologous to human MIEF1 (mitochondrial elongation factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Mief1 Products(3)

mRNA	Protein	Name
NM_001357659.1	NP_001344588.1	mitochondrial dynamics protein MID51 isoform 1
NM_001357660.1	NP_001344589.1	mitochondrial dynamics protein MID51 isoform 2
NM_178719.5	NP_848834.2	mitochondrial dynamics protein MID51 isoform 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	24508339	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	24508339	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of mitochondrial fission	IMP IMP: Inferred from mutant phenotype	23283981	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

mitochondrial dynamics protein MID51

Smith-Magenis syndrome chromosome region, candidate 7-like	mitochondrial dynamic protein MID51
mitochondrial dynamic protein of 51 kDa homolog	mitochondrial dynamics protein of 51 kDa homolog

Mief1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Mief1	Q8BGV8	Dnm1l	Mus musculus	Q8K1M6-3	GTPase Assay	24508339
Intra	Mief1	Q8BGV8	Dnm1l	Mus musculus	Q8K1M6-3	Solution Sedimentation	24508339
Intra	Mief1	Q8BGV8	Mief1	Mus musculus	Q8BGV8	X-Ray Diffraction	24508339
Intra	Mief1	Q8BGV8	Dnm1l	Mus musculus	Q8K1M6-3	TEM	24508339
Intra	Mief1	Q8BGV8	Mief1	Mus musculus	Q8BGV8	Anti Tag CoIP	24508339
Intra	Mief1	Q8BGV8	Dnm1l	Mus musculus	Q8K1M6-3	Anti Tag CoIP	24508339
Intra	Mief1	Q8BGV8	Dnm1l	Mus musculus	Q8K1M6-3	Y2H	24508339

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08439	MIEF1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mief1	NCBI	NCBI:54471

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