Mief1 - mitochondrial elongation factor 1 Gene

Also Known as Smcr7l; A230016E22

Species: Mus musculus

Gene Type: protein coding
Gene ID: 239555

Summary

Enables identical protein binding activity. Involved in positive regulation of mitochondrial fission. Located in mitochondrion. Orthologous to human MIEF1 (mitochondrial elongation factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Mief1 Products (3)

mRNA Protein Name
NM_001357659.1 NP_001344588.1 mitochondrial dynamics protein MID51 isoform 1
NM_001357660.1 NP_001344589.1 mitochondrial dynamics protein MID51 isoform 2
NM_178719.5 NP_848834.2 mitochondrial dynamics protein MID51 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
24508339 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24508339 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of mitochondrial fission IMP
IMP: Inferred from mutant phenotype
23283981 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial dynamics protein MID51

  • Smith-Magenis syndrome chromosome region, candidate 7-like

  • mitochondrial dynamic protein MID51

  • mitochondrial dynamic protein of 51 kDa homolog

  • mitochondrial dynamics protein of 51 kDa homolog

Mief1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Mief1 Q8BGV8 Dnm1l Mus musculus Q8K1M6-3
GTPase Assay
24508339
Intra
Mief1 Q8BGV8 Dnm1l Mus musculus Q8K1M6-3
Solution Sedimentation
24508339
Intra
Mief1 Q8BGV8 Mief1 Mus musculus Q8BGV8
X-Ray Diffraction
24508339
Intra
Mief1 Q8BGV8 Dnm1l Mus musculus Q8K1M6-3
TEM
24508339
Intra
Mief1 Q8BGV8 Mief1 Mus musculus Q8BGV8
Anti Tag CoIP
24508339
Intra
Mief1 Q8BGV8 Dnm1l Mus musculus Q8K1M6-3
Anti Tag CoIP
24508339
Intra
Mief1 Q8BGV8 Dnm1l Mus musculus Q8K1M6-3
Y2H
24508339
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08439 MIEF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mief1 NCBI NCBI:54471