Gpr161 - G protein-coupled receptor 161 Gene

Also Known as vl; Gm208; Gm208Gpr

Species: Mus musculus

Gene Type: protein coding
Gene ID: 240888

Summary

Enables G protein-coupled receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. Located in cilium and recycling endosome. Is expressed in several structures, including central nervous system; eye; and limb. Orthologous to human GPR161 (G protein-coupled receptor 161). [provided by Alliance of Genome Resources, Apr 2022]

Gpr161 Products (3)

mRNA Protein Name
NM_001081126.2 NP_001074595.1 G-protein coupled receptor 161 isoform 1
NM_001310429.1 NP_001297358.1 G-protein coupled receptor 161 isoform 2
NM_001310430.1 NP_001297359.1 G-protein coupled receptor 161 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled receptor activity IDA
IDA: Inferred from direct assay
23332756 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
28154160 MGI
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
23332756 MGI
involved in negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning IMP
IMP: Inferred from mutant phenotype
23332756 MGI
Cellular Component GO Annotation Evidence References Source
located in cilium IDA
IDA: Inferred from direct assay
23332756 MGI
located in glial cell projection IDA
IDA: Inferred from direct assay
28154160 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
28154160 MGI
located in recycling endosome IDA
IDA: Inferred from direct assay
23332756 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G-protein coupled receptor 161

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05677 GPR161 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19508 Gpr161 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26002 Gpr161 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr161 NCBI NCBI:23432