C4A - C4a complement C4A Gene

Also Known as C4; C4b; C4-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24233

Summary

Predicted to enable complement component C1q complex binding activity. Predicted to be involved in complement activation and positive regulation of apoptotic cell clearance. Located in extracellular space. Human ortholog(s) of this gene implicated in autistic disorder; autoimmune disease (multiple); complement deficiency (multiple); and renal cell carcinoma. Orthologous to several human genes including C4B (complement C4B (Chido blood group)). [provided by Alliance of Genome Resources, Apr 2022]

C4A Products (1)

mRNA Protein Name
NM_031504.3 NP_113692.2 complement C4 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
8805663 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
15634920 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement C4

  • complement C4-like

  • complement component 4 (within H-2S)

  • complement component 4, gene 1

  • complement component 4A (Rodgers blood group)

  • complement component 4B (Chido blood group)

  • complement component 4B (Childo blood group)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01745 C4A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W324243 11β-HSD1-IN-9 / Unkown
HY-RS18215 C4a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24692 C4a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens C4A NCBI NCBI:720
Mus musculus C4A NCBI NCBI:625018