Fbxl5 - F-box and leucine-rich repeat protein 5 Gene

Also Known as Fbl4; Fir4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 242960

Summary

Predicted to enable iron ion binding activity. Acts upstream of or within iron ion homeostasis and positive regulation of cellular protein catabolic process. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of SCF ubiquitin Ligase complex. Is expressed in central nervous system and retina. Orthologous to human FBXL5 (F-box and leucine rich repeat protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Fbxl5 Products (2)

mRNA Protein Name
NM_001159963.1 NP_001153435.1 F-box/LRR-repeat protein 5 isoform A
NM_178729.4 NP_848844.1 F-box/LRR-repeat protein 5 isoform B

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within multicellular organismal-level iron ion homeostasis IGI
IGI: Inferred from genetic interaction
21907140 MGI
acts upstream of or within multicellular organismal-level iron ion homeostasis IMP
IMP: Inferred from mutant phenotype
21907140 MGI
acts upstream of or within positive regulation of protein catabolic process IMP
IMP: Inferred from mutant phenotype
21907140 MGI
acts upstream of protein catabolic process IMP
IMP: Inferred from mutant phenotype
21907140 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-box/LRR-repeat protein 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04793 FBXL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20017 Fbxl5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26520 Fbxl5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fbxl5 NCBI NCBI:26234