Ppm1k - protein phosphatase 1K (PP2C domain containing) Gene

Also Known as PP2Cm; PP2C-kappa; 2900063A19Rik; A930026L03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 243382

Summary

Predicted to enable metal ion binding activity; protein serine Phosphatase activity; and protein threonine Phosphatase activity. Located in mitochondrion. Is expressed in several structures, including diaphragm; gut; heart; liver; and spleen. Used to study maple syrup urine disease. Human ortholog(s) of this gene implicated in maple syrup urine disease. Orthologous to human PPM1K (protein Phosphatase, Mg2+/Mn2+ dependent 1K). [provided by Alliance of Genome Resources, Apr 2022]

Ppm1k Products (1)

mRNA Protein Name
NM_175523.5 NP_780732.1 protein phosphatase 1K, mitochondrial precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of mitochondrial membrane permeability involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
17374715 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
17374715 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein phosphatase 1K, mitochondrial

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10968 PPM1K Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21696 Ppm1k Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28214 Ppm1k Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppm1k NCBI NCBI:152926