Tnfsf10 - TNF superfamily member 10 Gene

Also Known as Trail; Tnlg6a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246775

Summary

Predicted to enable several functions, including TRAIL binding activity; identical protein binding activity; and zinc ion binding activity. Involved in male gonad development; positive regulation of apoptotic process; and response to Insulin. Predicted to be located in extracellular space. Predicted to be integral component of membrane. Biomarker of osteoarthritis and polycystic ovary syndrome. Human ortholog(s) of this gene implicated in arteriosclerosis and small cell carcinoma. Orthologous to human TNFSF10 (TNF Superfamily member 10). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf10 Products (1)

mRNA Protein Name
NM_145681.2 NP_663714.2 tumor necrosis factor ligand superfamily member 10

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in male gonad development IEP
IEP: Inferred from expression pattern
12021051 RGD
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
19385008 RGD
involved in response to insulin IEP
IEP: Inferred from expression pattern
17352408 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor ligand superfamily member 10

  • tumor necrosis factor (ligand) superfamily, member 10

  • tumor necrosis factor ligand 6a

  • tumor necrosis factor superfamily member 10

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-181955 MS1129 / Unkown
HY-RS14818 TNFSF10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17568 Tnfsf10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24028 Tnfsf10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfsf10 NCBI NCBI:8743