Prkar2b - protein kinase cAMP-dependent type II regulatory subunit beta Gene

Also Known as RATDNA

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24679

Summary

Enables cAMP binding activity; cAMP-dependent protein kinase regulator activity; and protein domain specific binding activity. Involved in regulation of protein kinase activity; response to antipsychotic drug; and response to clozapine. Located in several cellular components, including membrane raft; neuronal cell body; and perinuclear region of cytoplasm. Part of cAMP-dependent protein kinase complex. Orthologous to human PRKAR2B (protein kinase cAMP-dependent type II regulatory subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Prkar2b Products (1)

mRNA Protein Name
NM_001030020.1 NP_001025191.1 cAMP-dependent protein kinase type II-beta regulatory subunit

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cAMP binding IDA
IDA: Inferred from direct assay
11907174 RGD
enables cAMP-dependent protein kinase regulator activity IDA
IDA: Inferred from direct assay
11907174 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
17610895 RGD
enables protein domain specific binding IDA
IDA: Inferred from direct assay
16996504 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of protein kinase activity IDA
IDA: Inferred from direct assay
11907174 RGD
involved in response to antipsychotic drug IEP
IEP: Inferred from expression pattern
11907174 RGD
Cellular Component GO Annotation Evidence References Source
part of cAMP-dependent protein kinase complex IDA
IDA: Inferred from direct assay
11907174 RGD
located in dendrite IDA
IDA: Inferred from direct assay
10618500 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
10618500 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
18550536 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cAMP-dependent protein kinase type II-beta regulatory subunit

  • Type II beta regulatory subunit of cAMP-dependent protein kinase

  • protein kinase cAMP-dependent type 2 regulatory subunit beta

  • protein kinase, cAMP dependent regulatory, type II beta

  • protein kinase, cAMP-dependent, regulatory subunit type II beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11115 PRKAR2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22021 Prkar2b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28539 Prkar2b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkar2b NCBI NCBI:5577