Wnt1 - Wnt family member 1 Gene

Also Known as Int1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24881

Summary

Predicted to enable cytokine activity; Frizzled binding activity; and protein domain specific binding activity. Involved in animal organ regeneration; cellular response to peptide hormone stimulus; and hepatocyte differentiation. Predicted to be located in cell surface; cytoplasm; and extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 15 and osteoporosis. Orthologous to human Wnt1 (Wnt family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Wnt1 Products (1)

mRNA Protein Name
NM_001105714.1 NP_001099184.1 proto-oncogene Wnt-1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in animal organ regeneration IMP
IMP: Inferred from mutant phenotype
20413689 RGD
involved in cellular response to peptide hormone stimulus IEP
IEP: Inferred from expression pattern
17400807 RGD
involved in hepatocyte differentiation IMP
IMP: Inferred from mutant phenotype
20413689 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proto-oncogene Wnt-1

  • Wingless-type MMTV integration site 1, homolog

  • wingless-related MMTV integration site 1

  • wingless-type MMTV integration site family, member 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-164528 SJ26 Inhibitor 98.65% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wnt1 NCBI NCBI:7471