Prkcb - protein kinase C, beta Gene

Rattus norvegicus

Also known as Pkcb; Prkcb1

Gene ID: 25023 | Gene type: protein coding

About Prkcb

Primary_assembly 1: 176,832,226-177,163,536 forward strand.mRatBN7.2:CM026974.1

This gene has 8 transcripts (splice variants), 287 orthologues, 9 paralogues and is associated with 25 phenotypes. Biased expression in Brain (RPKM 562.1), Spleen (RPKM 51.2) and 6 other tissues.

Summary

Enables protein kinase C activity. Involved in several processes, including dibenzo-p-dioxin metabolic process; positive regulation of odontogenesis of dentin-containing tooth; and response to vitamin D. Located in brush border membrane; centrosome; and cytosol. Used to study hyperglycemia; hypertension; and silicosis. Biomarker of congestive heart failure; obesity; and status epilepticus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and lung non-small cell carcinoma. Orthologous to human PRKCB (protein kinase C beta). [provided by Alliance of Genome Resources, Apr 2022]

Prkcb Products(2)

mRNA	Protein	Name
NM_012713.4	NP_036845.3	protein kinase C beta type isoform 1
NM_001172305.1	NP_001165776.1	protein kinase C beta type isoform 2

Prkcb Protein Structure

C1_cPKC_rpt1

C1_cPKC_rpt2

C2_PKC_alpha_gamma

STKc_cPKC_beta

0
200
400
600
673 a.a.

Protein Preferred Names

Protein Names

protein kinase C beta type

PKC-beta	protein kinase C beta I
protein kinase C beta II	protein kinase C, beta 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS11119	PRKCB Human Pre-designed siRNA Set A	/	Unkown
HY-RS11120	Prkcb Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS11121	Prkcb Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Prkcb	NCBI	NCBI:5579

Name
Email *

	Sorry, but the email address you supplied was invalid.