Dbi - diazepam binding inhibitor Gene

Also Known as Ep; Odn; Ttn; Acbp; Acoabp3; RNACOABP3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25045

Summary

Enables benzodiazepine receptor binding activity and fatty-acyl-CoA binding activity. Involved in several processes, including nervous system development; positive regulation of release of sequestered calcium ion into cytosol; and regulation of lipid metabolic process. Acts upstream of or within regulation of GABAergic synaptic transmission. Located in several cellular components, including contractile fiber; extracellular space; and synaptic vesicle. Orthologous to human DBI (diazepam binding inhibitor, acyl-CoA binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Dbi Products (1)

mRNA Protein Name
NM_031853.4 NP_114054.1 acyl-CoA-binding protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables benzodiazepine receptor binding IDA
IDA: Inferred from direct assay
6304714 RGD
enables fatty-acyl-CoA binding IPI
IPI: Inferred from physical interaction
11404184 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14530276 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to nutrient IEP
IEP: Inferred from expression pattern
15825833 RGD
involved in glial cell proliferation IDA
IDA: Inferred from direct assay
10899945 RGD
involved in negative regulation of fatty acid beta-oxidation IDA
IDA: Inferred from direct assay
11485163 RGD
involved in positive regulation of lipid biosynthetic process IDA
IDA: Inferred from direct assay
11485163 RGD
involved in positive regulation of release of sequestered calcium ion into cytosol IMP
IMP: Inferred from mutant phenotype
9804683 RGD
acts upstream of or within regulation of synaptic transmission, GABAergic IDA
IDA: Inferred from direct assay
3456171 RGD
Cellular Component GO Annotation Evidence References Source
located in contractile muscle fiber IDA
IDA: Inferred from direct assay
11812754 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
3819722 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
3819722 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acyl-CoA-binding protein

  • Diazepam binding inhibitor (GABA receptor modulator, acyl-Coenxyme A binding protein)

  • GABA receptor modulator

  • LRRGT00046

  • diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)

  • diazepam binding inhibitor (GABA receptor modulator

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101060 FGIN-1-43 98.96% Unkown
HY-RS15177 TSPO Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-162516 DBI-2 / Unkown
HY-RS03547 DBI Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17015 Dbi Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23458 Dbi Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dbi NCBI NCBI:1622
Mus musculus Dbi NCBI NCBI:13167