Gadd45a - growth arrest and DNA-damage-inducible, alpha Gene

Also Known as Ddit1; Gadd45

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25112

Summary

Predicted to enable several functions, including promoter-specific chromatin binding activity; protein N-terminus binding activity; and protein dimerization activity. Involved in G2/M transition of mitotic cell cycle. Predicted to be located in nuclear speck. Predicted to be active in cytoplasm and nucleus. Orthologous to human GADD45A (growth arrest and DNA damage inducible alpha). [provided by Alliance of Genome Resources, Apr 2022]

Gadd45a Products (1)

mRNA Protein Name
NM_024127.2 NP_077041.2 growth arrest and DNA damage-inducible protein GADD45 alpha

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in G2/M transition of mitotic cell cycle IEP
IEP: Inferred from expression pattern
11964479 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth arrest and DNA damage-inducible protein GADD45 alpha

  • DDIT-1

  • DNA damage-inducible transcript 1 protein

  • DNA-damage-inducible transcript 1

  • growth arrest and DNA-damage-inducible 45 alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-10587 BIX-01294 98.44% Unkown
HY-108239 BIX-01294 trihydrochloride 99.68% Unkown
HY-RS05229 GADD45A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-136893 SP-6-27 / Unkown
HY-RS17861 Gadd45a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24330 Gadd45a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gadd45a NCBI NCBI:1647