Sp4 - Sp4 transcription factor Gene

Also Known as HF-1b

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25162

Summary

Enables DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of heart contraction. Located in nucleus. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Orthologous to human SP4 (Sp4 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Sp4 Products (1)

mRNA Protein Name
NM_012761.2 NP_036893.1 transcription factor Sp4

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
15572681 RGD
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
12746457 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor Sp4

  • HF-1b zinc finger protein

  • trans-acting transcription factor 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (23)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-179528 DIM-3,5-Cl2 99.18% Unkown
HY-156277 SP4f Activator 99.77% Unkown
HY-156276 SP4e Activator 99.72% Unkown
HY-482945 (SP-4-1)-[[4,4′,4′′,4′′′-(21H,23H-Porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzenesulfonato]](6-)]cobaltate(3-) / Unkown
HY-RS13607 SP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W075610 Nickelate(4-), [[4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis[benzoato]](6-)-N21,N22,N23,N24]-, tetrahydrogen, (SP-4-1)- / Unkown
HY-W456409 (SP-4-1)-[5,10,15,20-Tetra-4-pyridinyl-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]nickel / Unkown
HY-W456534 Cuprate(4-), [[4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzoato]](6-)]-, (SP-4-1)- / Unkown
HY-W456551 Copper, [2,7,12,17-tetrakis(1,1-dimethylethyl)-21H,23H-porphyrazinato(2-)-κN21,κN22,κN23,κN24]-, (SP-4-1)- / Unkown
HY-W456552 (SP-4-1)-[5,10,15,20-Tetrakis(4-ethynylphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]zinc / Unkown
HY-W456554 Zincate(4-), [[4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzenesulfonato]](6-)]-, hydrogen (1:4), (SP-4-1)- / Unkown
HY-W456556 (SP-4-1)-[5,10,15,20-Tetraphenyl-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]tin / Unkown
HY-W456557 (SP-4-1)-[[4,4′,4′′,4′′′-(21H,23H-Porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzoato]](6-)]manganate(3-) / Unkown
HY-W456558 (SP-4-1)-[5,10,15,20-Tetrakis(4-methylphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]manganese / Unkown
HY-W456560 (SP-4-1)-[5,10,15,20-Tetrakis(4-methoxyphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]manganese / Unkown
HY-W543252 (SP-4-1)-[[4,4',4'',4'''-(21H,23H-Porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzoato]](6-)]cobaltate(4-) / Unkown
HY-W543724 (SP-4-1)-[5,10,15,20-Tetrakis(4-bromophenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]cobalt / Unkown
HY-W855971 (SP-4-1)-[29H,31H-phthalocyanine-2,9,16,23-tetracarboxylato(6-)-N29,N30,N31,N32]Nickelate(4-) / Unkown
HY-W855972 (SP-4-1)-[29H,31H-Phthalocyanine-2,9,16,23-tetracarboxylato(6-)-κN29,κN30,κN31,κN32]cobaltate(4-) / Unkown
HY-W855973 (SP-4-1)-[5,10,15,20-Tetrakis(4-bromophenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]copper / Unkown
HY-W855974 (SP-4-1)-[5,10,15,20-Tetrakis(4-bromophenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]nickel / Unkown
HY-RS18331 Sp4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24810 Sp4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sp4 NCBI NCBI:6671