Drd5 - dopamine receptor D5 Gene

Rattus norvegicus

Also known as D1B

Gene ID: 25195 | Gene type: protein coding

About Drd5

Primary_assembly 14: 72,489,347-72,490,774 reverse strand.mRatBN7.2:CM026987.1

This gene has 1 transcript (splice variant), 190 orthologues, 35 paralogues and is associated with 12 phenotypes.

Summary

Enables G-protein alpha-subunit binding activity and dopamine neurotransmitter receptor activity. Involved in several processes, including adenylate cyclase-activating Dopamine Receptor signaling pathway; negative regulation of protein kinase activity; and visual learning. Acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway. Located in several cellular components, including brush border membrane; dendritic spine; and neuronal cell body. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and blepharospasm. Orthologous to human DRD5 (Dopamine Receptor D5). [provided by Alliance of Genome Resources, Apr 2022]

Drd5 Products(1)

mRNA	Protein	Name
NM_012768.2	NP_036900.2	D(1B) dopamine receptor

Protein Preferred Names

Protein Names

D(1B) dopamine receptor

d(5) dopamine receptor	dopamine D5 receptor
dopamine receptor 5

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS04006	DRD5 Human Pre-designed siRNA Set A	/	Unkown
HY-RS04007	Drd5 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS04008	Drd5 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Drd5	NCBI	NCBI:1816

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