Anxa3 - annexin A3 Gene

Also Known as LC3; Anx3; LRRGT00047

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25291

Summary

Enables calcium-dependent phospholipid binding activity and Phospholipase A2 inhibitor activity. Involved in several processes, including animal organ regeneration; hippocampus development; and response to glucocorticoid. Located in axon; dendrite; and neuronal cell body. Biomarker of glaucoma. Orthologous to human AnxA3 (annexin A3). [provided by Alliance of Genome Resources, Apr 2022]

Anxa3 Products (1)

mRNA Protein Name
NM_012823.2 NP_036955.2 annexin A3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium-dependent phospholipid binding IDA
IDA: Inferred from direct assay
2968983 RGD
enables phospholipase A2 inhibitor activity IDA
IDA: Inferred from direct assay
2968983 RGD
Biological Process GO Annotation Evidence References Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
18182385 RGD
involved in hippocampus development IEP
IEP: Inferred from expression pattern
18493952 RGD
involved in positive regulation of DNA metabolic process IMP
IMP: Inferred from mutant phenotype
15744063 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
16819165 RGD
involved in response to growth factor IEP
IEP: Inferred from expression pattern
16819165 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
8725344 RGD
located in dendrite IDA
IDA: Inferred from direct assay
8725344 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
8725344 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

annexin A3

  • 35-alpha calcimedin

  • Annexin III (Lipocortin III)

  • PAP-III

  • annexin-3

  • lipocortin III

  • placental anticoagulant protein III

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-168951 (R)-SL18 Degrader / Unkown
HY-168950 ANXA3 degrader 1 Degrader / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Anxa3 NCBI NCBI:306