Htr4 - 5-hydroxytryptamine receptor 4 Gene
Species: Rattus norvegicus
About Htr4
This gene has 6 transcripts (splice variants), 201 orthologues, 35 paralogues and is associated with 10 phenotypes. Biased expression in Brain (RPKM 13.), Kidney (RPKM 3.6) and 4 other tissues.
Summary
Enables G protein-coupled serotonin receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and gamma-aminobutyric acid signaling pathway. Predicted to be located in cytoplasm and membrane. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Orthologous to human HTR4 (5-hydroxytryptamine receptor 4). [provided by Alliance of Genome Resources, Apr 2022]
Htr4 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_012853.2 | NP_036985.2 | 5-hydroxytryptamine receptor 4 |
Htr4 Protein Structure
7tmA_5-HT4: cd15056 (19 - 322)
7tmA_5-HT4: cd15056 (20 - 46)
7tmA_5-HT4: cd15056 (54 - 80)
7tmA_5-HT4: cd15056 (92 - 122)
7tmA_5-HT4: cd15056 (135 - 158)
7tmA_5-HT4: cd15056 (188 - 217)
7tmA_5-HT4: cd15056 (251 - 281)
7tmA_5-HT4: cd15056 (290 - 315)
- 0
- 100
- 200
- 300
- 388 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
5-hydroxytryptamine receptor 4 |
|
|
Related Agents
- Approval
- Pre-clinical Phase
Approval
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-14153A | Tegaserod maleate | 99.90% | Unkown | |
| HY-14153 | Tegaserod | 99.71% | Unkown |
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-14153S | Tegaserod-d11 | / | Unkown | |
| HY-RS06474 | HTR4 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS06475 | Htr4 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS06476 | Htr4 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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