GAGE1 - G antigen 1 Gene

Also Known as CT4.1; CT4.4; GAGE4; GAGE-1; GAGE-4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2543

About GAGE1

Cytogenetic location: Xp11.23 Genomic coordinates (GRCh38): X:49,599,013-49,608,538 (from NCBI)

This gene has 2 transcripts (splice variants), 30 orthologues and 22 paralogues. Restricted expression toward testis (RPKM 23.5).

Summary

This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several Other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

GAGE1 Products (1)

mRNA Protein Name
NM_001040663.4 NP_001035753.1 G antigen 1

GAGE1 Protein Structure

GAGE

GAGE: GAGE protein (1 - 117)

  • 0
  • 100
  • 139 a.a.
Protein Preferred Names Protein Names

G antigen 1

  • Cancer/testis antigen 4.4

Related Diseases

Diseases Alias
Melanoma

  • Malignant Melanoma

  • Cutaneous Melanoma

  • Naevocarcinoma

  • Malignant Melanomas
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05233 GAGE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown